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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620600
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nox4
Name: NADPH oxidase 4
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nox4increases expressionEXP 6480464CTDLead results in increased expression of NOX4 mRNAPMID:25596430
Nox4multiple interactionsEXP 6480464CTDSB 203580 inhibits the reaction [Lead results in increased expression of NOX4 mRNA]; U 0126 inhibits the reaction [Lead results in increased expression of NOX4 mRNA]PMID:25596430
Nox4decreases expressionISONOX4 (Homo sapiens)6480464CTDLead results in decreased expression of NOX4 mRNAPMID:37386098
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