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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62060
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ogt
Name: O-linked N-acetylglucosamine (GlcNAc) transferase
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ogtincreases expressionEXP 6480464CTDValproic Acid results in increased expression of OGT mRNAPMID:34779009
Ogtaffects expressionISOOGT (Homo sapiens)6480464CTDValproic Acid affects the expression of OGT mRNAPMID:25979313
Ogtdecreases expressionISOOGT (Homo sapiens)6480464CTDValproic Acid results in decreased expression of OGT mRNAPMID:23179753 PMID:27188386 PMID:28001369
Ogtmultiple interactionsISOOGT (Homo sapiens)6480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of OGT mRNAPMID:17183730
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