GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nox1 | increases expression | EXP | | 6480464 | CTD | Doxorubicin results in increased expression of NOX1 mRNA; Doxorubicin results in increased expression of NOX1 protein | PMID:16213474 PMID:24072175 PMID:24902966 PMID:35843304 | Nox1 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased expression of NOX1 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA]; Carvedilol inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA]; galangin inhibits the reaction [Doxorubicin results in increased expression of NOX1 protein]; pyrazolanthrone inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA]; Quercetin inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA]; Razoxane inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA]; rhodioloside inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA] | PMID:16213474 PMID:24072175 PMID:24902966 PMID:35843304 | Nox1 | increases expression | ISO | Nox1 (Mus musculus) | 6480464 | CTD | Doxorubicin results in increased expression of NOX1 mRNA; Doxorubicin results in increased expression of NOX1 protein | PMID:24072175 PMID:31158416 | Nox1 | multiple interactions | ISO | Nox1 (Mus musculus) | 6480464 | CTD | rhodioloside inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA] | PMID:24072175 | |
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