GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il12a | decreases expression | ISO | Il12a (Mus musculus) | 6480464 | CTD | Estradiol results in decreased expression of IL12A mRNA | PMID:19693291 | Il12a | increases expression | ISO | IL12A (Homo sapiens) | 6480464 | CTD | Estradiol results in increased expression of IL12A mRNA | PMID:36828454 | Il12a | multiple interactions | ISO | IL12A (Homo sapiens) | 6480464 | CTD | [Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]; Estradiol inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]]; Estradiol results in increased expression of [IL12A protein binds to IL12B protein] | PMID:20130130 | Il12a | multiple interactions | ISO | Il12a (Mus musculus) | 6480464 | CTD | [Estradiol co-treated with Progesterone] results in decreased expression of IL12A mRNA | PMID:19693291 | | ||||||||||||||||||||||
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