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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620559
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mt-nd4
Name: mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4
Acc ID: CHEBI:3000
Term: beauvericin
Definition: A trimeric cyclodepsipeptide composed from alternating methylphenylalanyl and hydroxyvaleryl residues.
Chemical ID: MESH:C004456
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mt-nd4decreases expressionISOMT-ND4 (Homo sapiens)6480464CTDbeauvericin results in decreased expression of ND4 mRNAPMID:29203277 PMID:31100301
Mt-nd4multiple interactionsISOMT-ND4 (Homo sapiens)6480464CTD[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ND4 mRNAPMID:31100301 PMID:34015425
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