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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620436
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cga
Name: glycoprotein hormones, alpha polypeptide
Acc ID: CHEBI:4042
Term: cypermethrin
Definition: A carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile.
Chemical ID: MESH:C017160
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7318386480464CTDcypermethrin results in increased expression of CGA mRNA

PMID:28731686, PMID:29149324
multiple interactionsISORGD:7318386480464CTD1, 2-bis(2-aminophenoxy)ethane N, N, N', N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [cypermethrin results in increased expression of CGA mRNA], 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3, 4-difluorobenzamide inhibits the reaction [cypermethrin results in increased expression of CGA mRNA], bisindolylmaleimide I inhibits the reaction [cypermethrin results in increased expression of CGA mRNA], Egtazic Acid inhibits the reaction [cypermethrin results in increased expression of CGA mRNA], Nimodipine inhibits the reaction [cypermethrin results in increased expression of CGA mRNA]

PMID:28731686, PMID:29149324
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.