GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Xdh | affects expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of XDH mRNA | PMID:22298810 PMID:34747641 | Xdh | decreases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of XDH mRNA | PMID:33387578 | Xdh | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of XDH mRNA | PMID:16054898 | Xdh | affects expression | ISO | Xdh (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of XDH mRNA | PMID:16962184 PMID:21570461 PMID:24680724 PMID:26377647 | Xdh | increases activity | ISO | XDH (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased activity of XDH protein | PMID:16226770 | Xdh | increases activity | ISO | Xdh (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased activity of XDH protein | PMID:11243847 PMID:21846477 | Xdh | increases expression | ISO | XDH (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of XDH mRNA | PMID:23152189 | Xdh | increases expression | ISO | Xdh (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of XDH mRNA | PMID:15251184 PMID:15328365 PMID:15800033 PMID:16611356 PMID:18796159 PMID:19770486 PMID:19933214 PMID:23864506 PMID:23994337 PMID:25270620 PMID:25975270 PMID:32553695 | Xdh | multiple interactions | ISO | XDH (Homo sapiens) | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with Mitomycin co-treated with Oxygen deficiency] affects the activity of XDH protein; [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased activity of XDH protein | PMID:16226770 | Xdh | multiple interactions | ISO | Xdh (Mus musculus) | 6480464 | CTD | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of XDH mRNA; AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of XDH protein]; Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of XDH mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [NFE2L2 gene mutant form results in decreased activity of XDH protein] | PMID:11243847 PMID:16054899 PMID:16214954 PMID:21846477 | |
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