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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62041
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Syt10
Name: synaptotagmin 10
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Syt10decreases expressionISOSyt10 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of SYT10 mRNAPMID:27195522
Syt10increases expressionISOSYT10 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of SYT10 mRNAPMID:22316170
Syt10increases methylationISOSYT10 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of SYT10 promoterPMID:27901495
Syt10multiple interactionsISOSyt10 (Mus musculus)6480464CTD[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of SYT10 mRNAPMID:27858113
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