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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620403
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccs
Name: copper chaperone for superoxide dismutase
Acc ID: CHEBI:30348
Term: 2,3,2-tetramine
Definition: A tetramine that has formula C7H20N4.
Chemical ID: MESH:C022177
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccsincreases expressionEXP 6480464CTD2,3,2-tetramine results in increased expression of CCS proteinPMID:12832419
Ccsincreases stabilityEXP 6480464CTD2,3,2-tetramine results in increased stability of CCS proteinPMID:12832419
Ccsmultiple interactionsEXP 6480464CTD[Copper Sulfate co-treated with 2,3,2-tetramine] results in increased degradation of CCS protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Copper Sulfate co-treated with 2,3,2-tetramine] results in increased degradation of CCS protein]; Copper Sulfate inhibits the reaction [2,3,2-tetramine results in increased expression of CCS protein]; lactacystin inhibits the reaction [[Copper Sulfate co-treated with 2,3,2-tetramine] results in increased degradation of CCS protein]PMID:12832419
Ccsincreases expressionISOCCS (Homo sapiens)6480464CTD2,3,2-tetramine results in increased expression of CCS proteinPMID:12832419
Ccsmultiple interactionsISOCCS (Homo sapiens)6480464CTDCopper Sulfate inhibits the reaction [2,3,2-tetramine results in increased expression of CCS protein]PMID:12832419
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