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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62037
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arc
Name: activity-regulated cytoskeleton-associated protein
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arcincreases expressionEXP 6480464CTDMethamphetamine results in increased expression of ARC mRNAPMID:11085305 PMID:19564919 PMID:20298714
Arcmultiple interactionsEXP 6480464CTDCTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA]PMID:11085305 PMID:20298714
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