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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:34688
Term: dichloroacetyl chloride
Definition: The acyl chloride obtained by displacement of the hydroxy group of dichloroacetic acid by chloride.
Chemical ID: MESH:C053063
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2decreases expressionISONfe2l2 (Mus musculus)6480464CTD2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 mRNA; 2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 proteinPMID:32073640
Nfe2l2multiple interactionsISONfe2l2 (Mus musculus)6480464CTD2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 protein]PMID:32073640
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