GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | decreases expression | EXP | | 6480464 | CTD | Endosulfan results in decreased expression of PTGS2 mRNA | PMID:29391264 | Ptgs2 | increases expression | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | Endosulfan results in increased expression of PTGS2 mRNA; Endosulfan results in increased expression of PTGS2 protein | PMID:25199686 | Ptgs2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Endosulfan results in increased expression of PTGS2 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Endosulfan results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Endosulfan results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Endosulfan results in increased expression of PTGS2 protein]; diphenyleneiodonium inhibits the reaction [Endosulfan results in increased expression of PTGS2 mRNA]; diphenyleneiodonium inhibits the reaction [Endosulfan results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [Endosulfan results in increased expression of PTGS2 protein] | PMID:25199686 | | ||||||||||||||||||||||
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