GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | increases expression | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | chromium hexavalent ion results in increased expression of PTGS2 mRNA; chromium hexavalent ion results in increased expression of PTGS2 protein | PMID:22472290 PMID:25448439 | Ptgs2 | increases expression | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | chromium hexavalent ion results in increased expression of PTGS2 mRNA; chromium hexavalent ion results in increased expression of PTGS2 protein | PMID:22472290 | Ptgs2 | multiple interactions | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | Luteolin inhibits the reaction [chromium hexavalent ion results in increased expression of PTGS2 mRNA]; Luteolin inhibits the reaction [chromium hexavalent ion results in increased expression of PTGS2 protein] | PMID:25448439 | Ptgs2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | [chromium hexavalent ion promotes the reaction [JUN protein binds to PTGS2 promoter]] which results in increased expression of PTGS2 mRNA; [chromium hexavalent ion promotes the reaction [RELA protein binds to PTGS2 promoter]] which results in increased expression of PTGS2 mRNA; chromium hexavalent ion promotes the reaction [JUN protein binds to PTGS2 promoter]; chromium hexavalent ion promotes the reaction [RELA protein binds to PTGS2 promoter]; IKBKB protein affects the reaction [chromium hexavalent ion results in increased expression of PTGS2 mRNA] | PMID:22472290 | |
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