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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620349
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:28640
Term: lipoteichoic acid
Definition: A teichoic acid which is covalently bound to a lipid.
Chemical ID: MESH:C009900
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2increases expressionEXP 6480464CTDlipoteichoic acid results in increased expression of PTGS2 proteinPMID:23500011
Ptgs2increases expressionISOPtgs2 (Mus musculus)6480464CTDlipoteichoic acid results in increased expression of PTGS2 proteinPMID:23500011
Ptgs2multiple interactionsISOPtgs2 (Mus musculus)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [lipoteichoic acid results in increased expression of PTGS2 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [lipoteichoic acid results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [lipoteichoic acid results in increased expression of PTGS2 protein]; oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine inhibits the reaction [lipoteichoic acid results in increased expression of PTGS2 protein]; prolinedithiocarbamate inhibits the reaction [lipoteichoic acid results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [lipoteichoic acid results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [lipoteichoic acid results in increased expression of PTGS2 protein]; tanshinone inhibits the reaction [lipoteichoic acid results in increased expression of PTGS2 protein]PMID:23500011
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