GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | increases expression | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | Nickel results in increased expression of PTGS2; Nickel results in increased expression of PTGS2 mRNA | PMID:21486220 PMID:24768652 PMID:25583101 | Ptgs2 | increases expression | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | Nickel analog results in increased expression of PTGS2 protein; Nickel results in increased expression of PTGS2 mRNA; Nickel results in increased expression of PTGS2 protein | PMID:19839048 PMID:22571318 PMID:27452194 | Ptgs2 | multiple interactions | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | CAT protein affects the reaction [Nickel results in increased expression of PTGS2]; NFATC4 mRNA affects the reaction [Nickel results in increased expression of PTGS2] | PMID:21486220 | Ptgs2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | Dexamethasone inhibits the reaction [Nickel results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [Nickel results in increased expression of PTGS2 mRNA] | PMID:19839048 | |
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