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GENE - TERM ANNOTATION REPORT

RGD ID: 62030
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Myh7
Name: myosin heavy chain 7
Acc ID: DOID:384
Term: Wolff-Parkinson-White syndrome
Definition: A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.
Definition Source(s): MESH:D014927
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Myh7 ISOMYH7 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Wolff-Parkinson-White patternPMID:10521296 PMID:11186938 PMID:11447480 PMID:12749056 PMID:15358028 PMID:15757018 PMID:16267253 PMID:16858239 PMID:17125710 PMID:18029407 PMID:18409188 PMID:18506004 PMID:19150014 PMID:19880069 PMID:20031618 PMID:20624503 PMID:20800588 PMID:20965760 PMID:21127202 PMID:21239446 PMID:21310275 PMID:21551322 PMID:21799269 PMID:22765922 PMID:22857948 PMID:22958901 PMID:22975586 PMID:23074333 PMID:23140321 PMID:23233322 PMID:23283745 PMID:23299917 PMID:23794396 PMID:24033266 PMID:24038877 PMID:24093860 PMID:24111713 PMID:24714796 PMID:24793961 PMID:25031304 PMID:25214167 PMID:25342278 PMID:25351510 PMID:25637381 PMID:25741868 PMID:26497160 PMID:26743238 PMID:26969327 PMID:27066506 PMID:27247418 PMID:27387980 PMID:27532257 PMID:27574918 PMID:27737317 PMID:27788187 PMID:27831900 PMID:27841901 PMID:28138913 PMID:28356264 PMID:28420666 PMID:28492532 PMID:28606303 PMID:28615295 PMID:28771489 PMID:28790153 PMID:28912206 PMID:29121657 PMID:29300372 PMID:29447731 PMID:30291343 PMID:30696458 PMID:30755392 PMID:30847666 PMID:30871747 PMID:31006259 PMID:31110529 PMID:31447099 PMID:31589614 PMID:32233023 PMID:32268277 PMID:33297573 PMID:33495597 PMID:33673806 PMID:7581410
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