GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ereg | decreases methylation | ISO | EREG (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of EREG promoter | PMID:27901495 | Ereg | increases expression | ISO | EREG (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of EREG mRNA | PMID:19181443 PMID:20064835 PMID:20106945 PMID:21632981 PMID:21871943 PMID:21887816 PMID:23625689 PMID:32234424 PMID:35870112 | Ereg | increases expression | ISO | Ereg (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of EREG mRNA | PMID:15894712 PMID:19770486 PMID:20713471 | Ereg | multiple interactions | ISO | EREG (Homo sapiens) | 6480464 | CTD | AHR protein affects the reaction [Benzo(a)pyrene results in increased expression of EREG mRNA] | PMID:20064835 | Ereg | multiple interactions | ISO | Ereg (Mus musculus) | 6480464 | CTD | [arsenite co-treated with Benzo(a)pyrene] results in increased expression of EREG mRNA | PMID:15894712 | |
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