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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620259
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eif4ebp1
Name: eukaryotic translation initiation factor 4E binding protein 1
Acc ID: CHEBI:50210
Term: 7-methyl-GTP
Definition: A guanosine 5'-phosphate that has formula C11H18N5O14P3.
Chemical ID: MESH:C017516
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif4ebp1affects bindingISOEIF4EBP1 (Homo sapiens)6480464CTDEIF4EBP1 protein binds to 7-methylguanosine triphosphatePMID:25940091
Eif4ebp1multiple interactionsISOEIF4EBP1 (Homo sapiens)6480464CTD1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one promotes the reaction [EIF4EBP1 protein binds to 7-methylguanosine triphosphate]; Sirolimus promotes the reaction [EIF4EBP1 protein binds to 7-methylguanosine triphosphate]PMID:25940091
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