GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cxcl10 | decreases expression | ISO | Cxcl10 (Mus musculus) | 6480464 | CTD | nickel sulfate results in decreased expression of CXCL10 mRNA | PMID:23445166 | Cxcl10 | increases expression | ISO | CXCL10 (Homo sapiens) | 6480464 | CTD | nickel sulfate results in increased expression of CXCL10 mRNA | PMID:12060402 | Cxcl10 | multiple interactions | ISO | CXCL10 (Homo sapiens) | 6480464 | CTD | [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of CXCL10 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL10 protein]]; nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased expression of CXCL10 mRNA]; nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL10 protein] | PMID:18096868 PMID:18832182 | | ||||||||||||||||||||||
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