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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620180
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc40a1
Name: solute carrier family 40 member 1
Acc ID: CHEBI:35154
Term: manganese(0)
Definition: An elemental manganese that has formula Mn.
Chemical ID: MESH:D008345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc40a1decreases expressionISOSlc40a1 (Mus musculus)6480464CTDManganese results in decreased expression of SLC40A1 mRNAPMID:29020610
Slc40a1increases exportISOSLC40A1 (Homo sapiens)6480464CTDSLC40A1 protein results in increased export of ManganesePMID:22178646
Slc40a1multiple interactionsISOSLC40A1 (Homo sapiens)6480464CTDCobalt inhibits the reaction [SLC40A1 protein results in increased export of Manganese]; Iron inhibits the reaction [SLC40A1 protein results in increased export of Manganese]; Nickel inhibits the reaction [SLC40A1 protein results in increased export of Manganese]PMID:22178646
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