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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620161
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp26a1
Name: cytochrome P450, family 26, subfamily a, polypeptide 1
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp26a1multiple interactionsEXP 6480464CTD[resveratrol co-treated with Streptozocin] results in increased expression of CYP26A1 mRNAPMID:25905778
Cyp26a1increases expressionISOCyp26a1 (Mus musculus)6480464CTDResveratrol results in increased expression of CYP26A1 mRNAPMID:29990529
Cyp26a1multiple interactionsISOCYP26A1 (Homo sapiens)6480464CTD[Plant Extracts co-treated with Resveratrol] results in decreased expression of CYP26A1 mRNAPMID:23557933
Cyp26a1multiple interactionsISOCyp26a1 (Mus musculus)6480464CTD6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol results in increased expression of CYP26A1 mRNA]; Resveratrol inhibits the reaction [titanium dioxide results in decreased expression of CYP26A1 mRNA]PMID:29990529 PMID:31298478
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