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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620160
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bid
Name: BH3 interacting domain death agonist
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bidmultiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [7-ketocholesterol results in decreased expression of BID protein]PMID:25845326
Bidmultiple interactionsISOBID (Homo sapiens)6480464CTD[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [sanguinarine results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BID protein]PMID:16169029 PMID:17574045 PMID:21310227 PMID:23660334 PMID:23711929 PMID:25034532 PMID:30408460
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