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GENE - TERM ANNOTATION REPORT

RGD ID: 620156
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ank2
Name: ankyrin 2
Acc ID: DOID:0060224
Term: atrial fibrillation
Definition: A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Atrial_fibrillation "DO" "DO", http://www.mayoclinic.org/diseases-conditions/atrial-fibrillation/basics/definition/con-20027014 "DO" "DO", http://www.nhlbi.nih.gov/health/health-topics/topics/af "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ank2 ISOAnk2 (Mus musculus) or ANK2 (Homo sapiens)6767284RGD  
Ank2onsetISOANK2 (Homo sapiens)9068941RGD PMID:21859974 REF_RGD_ID:6767284
Ank2 ISOANK2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Atrial fibrillationPMID:17161064 PMID:23861362 PMID:24448499 PMID:25649125 PMID:25741868 PMID:26159999 PMID:28492532
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