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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620103
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bad
Name: BCL2-associated agonist of cell death
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baddecreases expressionEXP 6480464CTDOxygen deficiency results in decreased expression of BAD protein modified formPMID:29139225
Badincreases expressionEXP 6480464CTDOxygen deficiency results in increased expression of BAD mRNA; Oxygen deficiency results in increased expression of BAD protein modified formPMID:26476374 PMID:29139225
Badmultiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of BAD mRNA]; Tea inhibits the reaction [Oxygen deficiency results in decreased expression of BAD protein modified form]; Tea inhibits the reaction [Oxygen deficiency results in increased expression of BAD protein modified form]PMID:26476374 PMID:29139225
Badmultiple interactionsISOBAD (Homo sapiens)6480464CTDOxygen affects the reaction [AHR protein results in decreased expression of BAD mRNA]PMID:27103661
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