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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620089
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ocln
Name: occludin
Acc ID: CHEBI:17963
Term: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Definition: A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
Chemical ID: MESH:D015632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Oclndecreases expressionISOOcln (Mus musculus)6480464CTD1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of OCLN proteinPMID:31351185
Oclnmultiple interactionsISOOcln (Mus musculus)6480464CTD[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of OCLN protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of OCLN protein]PMID:25064079
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