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GENE - TERM ANNOTATION REPORT

RGD ID: 620063
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ilk
Name: integrin-linked kinase
Acc ID: GO:0005925
Term: focal adhesion
Definition: A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ).
Definition Source(s): GOC:aruk, GOC:bc, ISBN:0124325653, ISBN:0815316208, PMID:10419689, PMID:12191915, PMID:15246682, PMID:1643657, PMID:16805308, PMID:19197329, PMID:23033047, PMID:26923917, PMID:28796323, PMID:8314002
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ilk IDA 2301740RGD  
Ilk IDA 2302069RGD  
Ilk IDA 2302070RGD  
Ilklocated_inISOILK (Homo sapiens)1624291RGD PMID:30254023

PMID:30254023
Ilklocated_inISOILK (Homo sapiens) or UniProtKB:Q13418-1 or UniProtKB:Q13418-31624291RGD GO_REF:0000052
Ilklocated_inISOIlk (Mus musculus)1624291RGD MGI:2447522 PMID:12432066 MGI:3511711 PMID:15565145 MGI:5504320 PMID:23658024

MGI:2447522 MGI:3511711 MGI:5504320 PMID:12432066 PMID:15565145 PMID:23658024
Ilkis_active_inIBAFB:FBgn0028427 or MGI:1195267 or PANTHER:PTN001510364 or Ilk (Rattus norvegicus) or UniProtKB:Q134181600115GO_CentralGO_REF:0000033

GO_REF:0000033
Ilklocated_inIDA 633110MGIPMID:11304546

 
Ilklocated_inIEAUniProtKB-SubCell:SL-01181600115UniProtGO_REF:0000044

GO_REF:0000044
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