GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Prdx3 | decreases expression | ISO | Prdx3 (Mus musculus) | 6480464 | CTD | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of PRDX3 protein | PMID:23562983 | Prdx3 | increases expression | ISO | Prdx3 (Mus musculus) | 6480464 | CTD | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of PRDX3 mRNA | PMID:20230807 | Prdx3 | multiple interactions | ISO | Prdx3 (Mus musculus) | 6480464 | CTD | [Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of PRDX3 mRNA; Levodopa inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of PRDX3 protein]; Minocycline inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of PRDX3 protein]; Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of PRDX3 mRNA]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of PRDX3 protein] | PMID:20230807 PMID:23562983 | |
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