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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62001
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Muc5ac
Name: mucin 5AC, oligomeric mucus/gel-forming
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Muc5acmultiple interactionsEXP 6480464CTDResveratrol inhibits the reaction [EGF protein results in increased expression of MUC5AC mRNA]; Resveratrol inhibits the reaction [EGF protein results in increased expression of MUC5AC protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC protein]; Resveratrol inhibits the reaction [TNF protein results in increased expression of MUC5AC mRNA]; Resveratrol inhibits the reaction [TNF protein results in increased expression of MUC5AC protein]PMID:22213337
Muc5acdecreases expressionISOMUC5AC (Homo sapiens)6480464CTDResveratrol results in decreased expression of MUC5AC proteinPMID:26549244
Muc5acmultiple interactionsISOMuc5ac (Mus musculus)6480464CTDResveratrol inhibits the reaction [OVAL protein results in increased expression of MUC5AC mRNA]; Resveratrol inhibits the reaction [OVAL protein results in increased expression of MUC5AC protein]PMID:26549244
Muc5acmultiple interactionsISOMUC5AC (Homo sapiens)6480464CTDResveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC mRNA]; Resveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC protein]; Resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of MUC5AC mRNA]PMID:20709182 PMID:33421718
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