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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:33853
Term: phenols
Definition: Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.
Chemical ID: MESH:D010636
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfadecreases response to substanceISOVEGFA (Homo sapiens)6480464CTDPhenols results in decreased susceptibility to VEGFA proteinPMID:16580641
Vegfamultiple interactionsISOVEGFA (Homo sapiens)6480464CTDPhenols inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK1 protein]; Phenols inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK3 protein]PMID:16580641
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