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GENE - TERM ANNOTATION REPORT

RGD ID: 619989
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ido1
Name: indoleamine 2,3-dioxygenase 1
Acc ID: DOID:14115
Term: toxic shock syndrome
Definition: A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Toxic_shock_syndrome "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ido1severityISOIDO1 (Homo sapiens)39939075RGDprotein:increased activity, increased expression:plasma, heart (human) 
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