GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hdac2 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of HDAC2 mRNA | PMID:25181051 | Hdac2 | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of HDAC2 mRNA; bisphenol A results in increased expression of HDAC2 protein | PMID:30816183 PMID:34838597 | Hdac2 | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of HDAC2 mRNA; HDAC2 mutant form inhibits the reaction [bisphenol A results in decreased expression of SLC12A5 mRNA]; trichostatin A inhibits the reaction [bisphenol A results in increased expression of HDAC2 protein] | PMID:23440186 PMID:34838597 PMID:36041667 | Hdac2 | affects expression | ISO | HDAC2 (Homo sapiens) | 6480464 | CTD | bisphenol A affects the expression of HDAC2 mRNA | PMID:33670352 | Hdac2 | affects methylation | ISO | Hdac2 (Mus musculus) | 6480464 | CTD | bisphenol A affects the methylation of HDAC2 promoter | PMID:27334623 | Hdac2 | decreases expression | ISO | HDAC2 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of HDAC2 protein | PMID:37567409 | Hdac2 | decreases expression | ISO | Hdac2 (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of HDAC2 mRNA | PMID:33221593 | Hdac2 | increases expression | ISO | Hdac2 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of HDAC2 mRNA; bisphenol A results in increased expression of HDAC2 protein | PMID:24333847 PMID:28496034 PMID:34655688 | Hdac2 | multiple interactions | ISO | Hdac2 (Mus musculus) | 6480464 | CTD | HDAC2 protein affects the reaction [bisphenol A results in decreased expression of CCND1 mRNA]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of CCND1 protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of CHAT protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of CTNNB1 mRNA]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of CTNNB1 protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of DLG4 mRNA]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of DLG4 protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of FURIN protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of GRIN1 mRNA]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of GRIN1 protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of MYC mRNA]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of MYC protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of NTRK1 protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of SLC17A6 mRNA]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of SLC17A6 protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of SPN mRNA]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of SPN protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of SYP mRNA]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of SYP protein]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of WNT3A mRNA]; HDAC2 protein affects the reaction [bisphenol A results in decreased expression of WNT3A protein]; HDAC2 protein affects the reaction [bisphenol A results in increased activity of and results in decreased phosphorylation of GSK3B protein]; HDAC2 protein affects the reaction [bisphenol A results in increased expression of ACHE mRNA alternative form]; HDAC2 protein affects the reaction [bisphenol A results in increased expression of ACHE mRNA]; HDAC2 protein affects the reaction [bisphenol A results in increased expression of and results in decreased metabolism of NGF protein]; HDAC2 protein affects the reaction [bisphenol A results in increased expression of NGF mRNA]; HDAC2 protein affects the reaction [bisphenol A results in increased expression of NGFR protein] | PMID:34655688 PMID:37372067 | |
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