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GENE - TERM ANNOTATION REPORT

RGD ID: 61995
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pten
Name: phosphatase and tensin homolog
Acc ID: DOID:5082
Term: liver cirrhosis
Definition: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Definition Source(s): MESH:D008103
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pten ISOPten (Mus musculus)127285596RGDassociated with schistosomiasis;protein, mRNA:decreased expression:liver (mouse) 
Pten ISOPTEN (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:26023714
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