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GENE - TERM ANNOTATION REPORT

RGD ID: 619930
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb11
Name: ATP binding cassette subfamily B member 11
Acc ID: GO:0015722
Term: canalicular bile acid transport
Definition: Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
Definition Source(s): GOC:dph
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb11 IDA 728120RGD  
Abcb11involved_inISOABCB11 (Canis lupus familiaris)1624291RGD PMID:20398791

PMID:20398791
Abcb11involved_inISOABCB11 (Homo sapiens)1624291RGD PMID:20398791 PMID:22262466 PMID:32203132

PMID:20398791 PMID:22262466 PMID:32203132
Abcb11involved_inISOAbcb11 (Mus musculus)1624291RGD MGI:1930837 PMID:11172067 MGI:5442473 PMID:22619174 MGI:5543985 PMID:23764895 MGI:6436413 PMID:20398791

MGI:1930837 MGI:5442473 MGI:5543985 MGI:6436413 PMID:11172067 PMID:20398791 PMID:22619174 PMID:23764895
Abcb11involved_inIEAUniProtKB:O95342 or ensembl:ENSP000004979311600115EnsemblGO_REF:0000107

GO_REF:0000107
Abcb11involved_inIEAUniProtKB:Q9QY30 or ensembl:ENSMUSP000000997701600115EnsemblGO_REF:0000107

GO_REF:0000107
Abcb11involved_inIBAMGI:1351619 or PANTHER:PTN002795062 or Abcb11 (Rattus norvegicus) or UniProtKB:B8K1W2 or UniProtKB:O953421600115GO_CentralGO_REF:0000033

GO_REF:0000033
Abcb11involved_inIMP 30309945UniProtPMID:20398791

 
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