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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619868
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gclc
Name: glutamate-cysteine ligase, catalytic subunit
Acc ID: CHEBI:30512
Term: silver atom
Definition: A copper group element atom that has formula Ag.
Chemical ID: MESH:D012834
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gclcincreases expressionISOGclc (Mus musculus)6480464CTDSilver results in increased expression of GCLC mRNAPMID:27131904
Gclcincreases expressionISOGCLC (Homo sapiens)6480464CTDSilver results in increased expression of GCLC mRNAPMID:22036727 PMID:22546375 PMID:26014281
Gclcmultiple interactionsISOGCLC (Homo sapiens)6480464CTDNFE2L2 protein affects the reaction [Silver results in increased expression of GCLC mRNA]PMID:22546375
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