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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619864
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gabbr2
Name: gamma-aminobutyric acid type B receptor subunit 2
Acc ID: CHEBI:45951
Term: trifluoperazine
Definition: A member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
Chemical ID: MESH:D014268
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabbr2multiple interactionsISOGABBR2 (Homo sapiens)6480464CTDTrifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]PMID:15627515
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