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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fas
Name: Fas cell surface death receptor
Acc ID: CHEBI:80043
Term: Nodularin
Definition: An ether that has formula C41H60N8O10.
Chemical ID: MESH:C063998
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasincreases expressionISOFAS (Homo sapiens)6480464CTDnodularin results in increased expression of FAS mRNA; nodularin results in increased expression of FAS proteinPMID:21262250
Fasmultiple interactionsISOFAS (Homo sapiens)6480464CTDRELA mutant form inhibits the reaction [nodularin results in increased expression of FAS mRNA]; RELA mutant form inhibits the reaction [nodularin results in increased expression of FAS protein]PMID:21262250
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