GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619787
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpc5
Name: transient receptor potential cation channel, subfamily C, member 5
Acc ID: CHEBI:60479
Term: lysophosphatidylcholine
Definition: An acylglycerophosphocholine resulting from partial hydrolysis of a phosphatidylcholine, which removes one of the fatty acyl groups. The structure is depicted in the image where R1 = acyl, R2 = H or where R1 = H, R2 = acyl.
Chemical ID: MESH:D008244
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7333346480464CTDLysophosphatidylcholines promotes the reaction [TRPC5 protein results in increased transport of Calcium]

resveratrol inhibits the reaction [Lysophosphatidylcholines promotes the reaction [TRPC5 protein results in increased transport of Calcium]]

PMID:21127073
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.