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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619757
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acox1
Name: acyl-CoA oxidase 1
Acc ID: CHEBI:51348
Term: tetraphene
Definition: An angular ortho-fused polycyclic arene consisting of four fused benzene rings.
Chemical ID: MESH:C030935
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acox1increases expressionISOAcox1 (Mus musculus)6480464CTDbenz(a)anthracene results in increased expression of ACOX1 mRNA; benz(a)anthracene results in increased expression of ACOX1 proteinPMID:10497882
Acox1multiple interactionsISOAcox1 (Mus musculus)6480464CTDbenz(a)anthracene promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]PMID:10497882
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