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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619756
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bbox1
Name: gamma-butyrobetaine hydroxylase 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bbox1increases expressionEXP 6480464CTDValproic Acid results in increased expression of BBOX1 mRNAPMID:35594946
Bbox1affects expressionISOBBOX1 (Homo sapiens)6480464CTDValproic Acid affects the expression of BBOX1 mRNAPMID:30008028
Bbox1decreases methylationISOBBOX1 (Homo sapiens)6480464CTDValproic Acid results in decreased methylation of BBOX1 genePMID:29154799
Bbox1increases expressionISOBBOX1 (Homo sapiens)6480464CTDValproic Acid results in increased expression of BBOX1 mRNAPMID:29154799
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