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GENE - TERM ANNOTATION REPORT

RGD ID: 619745
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh13
Name: cadherin 13
Acc ID: DOID:684
Term: hepatocellular carcinoma
Definition: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
Definition Source(s): MESH:D006528, http://cancergenome.nih.gov/cancersselected/LiverHepatocellularCarcinoma, http://en.wikipedia.org/wiki/Hepatocellular_carcinoma, http://www.omim.org/entry/114550
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 ISORGD:73437411554173CTDCTD Direct Evidence: marker/mechanism

PMID:18425332, PMID:18553387, PMID:28284560
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.