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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619745
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh13
Name: cadherin 13
Acc ID: CHEBI:76995
Term: alpha-naphthoflavone
Definition: An extended flavonoid resulting from the formal fusion of a benzene ring with the h side of flavone. A synthetic compound, it is an inhibitor of aromatase (EC 1.14.14.14).
Chemical ID: MESH:C011512
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDAHR protein promotes the reaction [alpha-naphthoflavone results in decreased expression of CDH13 mRNA], alpha-naphthoflavone inhibits the reaction [9, 10-Dimethyl-1, 2-benzanthracene results in decreased expression of CDH13 mRNA], alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDH13 mRNA], alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDH13 mRNA]

PMID:12559965
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.