GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Lrp4 | affects expression | ISO | Lrp4 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of LRP4 mRNA | PMID:21570461 PMID:26377647 | Lrp4 | increases expression | ISO | Lrp4 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of LRP4 mRNA | PMID:18796159 PMID:19770486 PMID:19933214 PMID:21889950 PMID:25270620 PMID:25975270 PMID:26290441 PMID:28922406 | Lrp4 | increases expression | ISO | LRP4 (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of LRP4 mRNA | PMID:29704546 | Lrp4 | multiple interactions | ISO | Lrp4 (Mus musculus) | 6480464 | CTD | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of LRP4 mRNA; [Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of LRP4 mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of LRP4 mRNA | PMID:16214954 PMID:25975270 PMID:28433925 | Lrp4 | multiple interactions | ISO | LRP4 (Homo sapiens) | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in increased expression of LRP4 mRNA | PMID:29704546 | |
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