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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61968
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnj2
Name: potassium inwardly-rectifying channel, subfamily J, member 2
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnj2affects expressionISOKCNJ2 (Homo sapiens)6480464CTDDoxorubicin affects the expression of KCNJ2 mRNAPMID:25529476
Kcnj2increases expressionISOKCNJ2 (Homo sapiens)6480464CTDDoxorubicin results in increased expression of KCNJ2 mRNAPMID:26537877 PMID:28940058 PMID:30031762
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