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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61965
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptpn1
Name: protein tyrosine phosphatase, non-receptor type 1
Acc ID: CHEBI:7903
Term: pamidronate
Definition: null
Chemical ID: MESH:C019248
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptpn1multiple interactionsISOPTPN1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]]; Acetylcysteine inhibits the reaction [Pamidronate promotes the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]]; Acetylcysteine inhibits the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]; Arsenic Trioxide promotes the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]; Pamidronate promotes the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]; Pamidronate results in decreased expression of and results in decreased activity of PTPN1 proteinPMID:32337366
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