Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619574
Species: Homo sapiens
RGD Object: Gene
Symbol: GFAP
Name: glial fibrillary acidic protein
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GFAPincreases expressionEXP 6480464CTDCapsaicin results in increased expression of GFAP mRNAPMID:18405923
GFAPincreases expressionISOGfap (Rattus norvegicus)6480464CTDCapsaicin results in increased expression of GFAP proteinPMID:20826152
GFAPmultiple interactionsISOGfap (Rattus norvegicus)6480464CTD7-nitroindazole inhibits the reaction [Capsaicin results in increased expression of GFAP protein]; [7-nitroindazole co-treated with pimagedine] promotes the reaction [Capsaicin results in increased expression of GFAP protein]; Capsaicin inhibits the reaction [IL6 protein results in increased expression of GFAP mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]; pimagedine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]PMID:19285962 PMID:20826152
Go Back to source page   Continue to Ontology report