GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GFAP | decreases expression | EXP | | 6480464 | CTD | Folic Acid results in decreased expression of GFAP mRNA | PMID:21867686 | GFAP | decreases expression | ISO | Gfap (Mus musculus) | 6480464 | CTD | Folic Acid results in decreased expression of GFAP mRNA | PMID:25629700 | GFAP | multiple interactions | ISO | Gfap (Mus musculus) | 6480464 | CTD | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GFAP gene; Folic Acid inhibits the reaction [Methotrexate results in decreased expression of GFAP mRNA]; Folic Acid inhibits the reaction [Methotrexate results in decreased expression of GFAP protein] | PMID:20938992 PMID:30502384 | GFAP | multiple interactions | ISO | Gfap (Rattus norvegicus) | 6480464 | CTD | Folic Acid inhibits the reaction [Methotrexate results in decreased expression of GFAP mRNA] | PMID:30502384 | |
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