GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk3 | multiple interactions | EXP | | 6480464 | CTD | [cypermethrin results in decreased susceptibility to Dihydrotestosterone] which results in decreased phosphorylation of MAPK3 protein | PMID:30974244 | Mapk3 | multiple interactions | ISO | Mapk3 (Rattus norvegicus) | 6480464 | CTD | [Dihydrotestosterone co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein; bisphenol A inhibits the reaction [[Dihydrotestosterone co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein] | PMID:30707916 | Mapk3 | multiple interactions | ISO | MAPK3 (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dihydrotestosterone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Dihydrotestosterone results in increased activity of AR protein mutant form] which results in increased phosphorylation of MAPK3 protein; AR protein promotes the reaction [Dihydrotestosterone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bicalutamide inhibits the reaction [Dihydrotestosterone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Dihydrotestosterone results in increased phosphorylation of and results in increased activity of MAPK3 protein | PMID:15466214 PMID:18819937 | |
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