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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619570
Species: Homo sapiens
RGD Object: Gene
Symbol: MAPK3
Name: mitogen-activated protein kinase 3
Acc ID: CHEBI:38957
Term: 4,4'-thiodiphenol
Definition: A phenol that has formula C12H10O2S.
Chemical ID: MESH:C586730
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAPK3increases phosphorylationEXP 6480464CTDbis(4-oxyphenyl)sulfide results in increased phosphorylation of MAPK3 proteinPMID:27880919
MAPK3multiple interactionsEXP 6480464CTD4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bis(4-oxyphenyl)sulfide results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [bis(4-oxyphenyl)sulfide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [bis(4-oxyphenyl)sulfide results in increased phosphorylation of MAPK3 protein]; Wortmannin inhibits the reaction [bis(4-oxyphenyl)sulfide results in increased phosphorylation of MAPK3 protein]PMID:27880919
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