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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619570
Species: Homo sapiens
RGD Object: Gene
Symbol: MAPK3
Name: mitogen-activated protein kinase 3
Acc ID: CHEBI:34027
Term: 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
Definition: A diarylmethane that has formula C14H9Cl5.
Chemical ID: MESH:C016340
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAPK3increases phosphorylationEXP 6480464CTDo,p'-DDT results in increased phosphorylation of MAPK3 proteinPMID:11222871 PMID:20678559 PMID:34167450
MAPK3multiple interactionsEXP 6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [o,p'-DDT results in increased phosphorylation of MAPK3 protein]PMID:20678559
MAPK3multiple interactionsISOMapk3 (Mus musculus)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [o,p'-DDT results in increased phosphorylation of and results in increased activity of MAPK3 protein]; o,p'-DDT results in increased phosphorylation of and results in increased activity of MAPK3 proteinPMID:18840457
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