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GENE - TERM ANNOTATION REPORT

RGD ID: 61957
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Isl1
Name: ISL LIM homeobox 1
Acc ID: GO:0060037
Term: pharyngeal system development
Definition: The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the structure it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.
Definition Source(s): GOC:dph
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Isl1involved_inISOIsl1 (Mus musculus)1624291RGDUniProtKB:Q02248 MGI:3829137 PMID:17519333

MGI:3829137 PMID:17519333
Isl1involved_inIEAUniProtKB:P61372 or ensembl:ENSMUSP000000448791600115EnsemblGO_REF:0000107

GO_REF:0000107
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